2024
- PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization.
Ito J, Nakamura T, Toyama T, Chen D, Berndt C, Poschmann G, Mourão ASD, Doll S, Suzuki M, Zhang W, Zheng J, Trümbach D, Yamada N, Ono K, Yazaki M, Kawai Y, Arisawa M, Ohsaki Y, Shirakawa H, Wahida A, Proneth B, Saito Y, Nakagawa K, Mishima E*, Conrad M*
Mol Cell. 2024 Nov 5:S1097-2765(24)00868-2. doi: 10.1016/j.molcel.2024.10.028. Online ahead of print. (*equal contribution).
- Calcium signals as regulators of ferroptosis in cancerIoana Stejerean-Todoran, Christine S. Gibhardt, Ivan Bogeski.
Cell Calcium 2024, 102966, DOI: 10.1016/j.ceca.2024.102966
- STING orchestrates the neuronal inflammatory stress response in multiple sclerosis
Woo MS, Mayer C, Binkle-Ladisch L, Sonner JK, Rosenkranz SC, Shaposhnykov A, Rothammer N, Tsvilovskyy V, Lorenz SM, Raich L, Bal LC, Vieira V, Wagner I, Bauer S, Glatzel M, Conrad M, Merkler D, Freichel M, Friese MA
Cell. 2024 Jun 7:S0092-8674(24)00576-2. doi: 10.1016/j.cell.2024.05.031. Online ahead of print.
- Ferroptosis in Health and Disease
Carsten Berndt, Hamed Alborzinia, Vera Skafar Amen, Scott Aytone, Uladzimir Barayeu, Alexander Bartelt, Hülya Bayir, Christina M. Bebber, Kivanc Birsoym, Jan P. Böttcher, Simone Brabletz, Thomas Brabletz, Ashley R. Brown, Bernhard Brüne, Giorgia Bulli, Alix Bruneau, Quan Chent, Gina M. DeNicolau, Tobias P. Dick, Ayelén Distéfano, Scott Dixon, Jan Broder Engler, Julia Esser-von Bieren, Maria Fedorova, José Pedro Friedmann Angeli, Manuel A. Friese, Dominic C. Fuhrmann, Ana J. García-Sáez, Karolina Garbowicz, Magdalena Götz, Wei Guae, Linda Hammerich, Behrouz Hassannia, Xuejun Jiang, Aicha Jeridi, Jun Pyo Kang, Valerian E Kagan, David B. Konrad, Stefan Kotschi, Peng Lei, Marlene le-Tertre, Sima Lev, Deguang Liang, Andreas Linkermann, Carolin Lohr, Svenja Lorenz, Tom Lüdde, Axel Methner, Bernhard Michalkeau, Anna V. Milton, Junxia Min, Eikan Mishima, Sebastian Müller, Hozumi Motohashi, Martina Muckenthaler, Shohei Murakami, James A. Olzmann, Gabriela Pagnuss, Zijan Pan, Thales Papagiannakopoulos, Lohans Pedrera Puentes, Derek A. Pratt, Bettina Proneth, Lukas Ramsauer, Raphael Rodriguez, Yoshiro Saito, Felix Schmidt, Carina Schmitt, Almut Schulze, Annemarie Schwab, Anna Schwantes, Mariluz Soul, Benedikt Spitzlberger, Brent R. Stockwell, Leonie Thewes, Oliver Thorn-Seshold, Shinya Toyokuni, Wulf Tonnus, Andreas Trumpp, Peter Vandenabeele, Tom Vanden Berghe, Vivek Vikantaramani, Felix C. E. Vogel, Silvia von Karstedt, Fudi Wang, Frank Westermann, Michele Wölk, Katherine Wu, Xin Yang, Fan Yu, Yilong Zou, and Marcus Conrad
Redox Biology May 24
- PGE2 inhibits TIL expansion by disrupting IL-2 signalling and mitochondrial function.
Morotti M, Grimm AJ, Hope HC, Arnaud M, Desbuisson M, Rayroux N, Barras D, Masid M, Murgues B, Chap BS, Ongaro M, Rota IA, Ronet C, Minasyan A, Chiffelle J, Lacher SB, Bobisse S, Murgues C, Ghisoni E, Ouchen K, Bou Mjahed R, Benedetti F, Abdellaoui N, Turrini R, Gannon PO, Zaman K, Mathevet P, Lelievre L, Crespo I, Conrad M, Verdeil G, Kandalaft LE, Dagher J, Corria-Osorio J, Doucey MA, Ho PC, Harari A, Vannini N, Böttcher JP, Dangaj Laniti D, Coukos G.
Nature. 2024 May;629(8011):426-434. doi: 10.1038/s41586-024-07352-w. Epub 2024 Apr 24. PMID: 38658764 Free PMC article.
- PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells.
Lacher SB, Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP.
Nature. 2024 May;629(8011):417-425. doi: 10.1038/s41586-024-07254-x. Epub 2024 Apr 24. PMID: 38658748 Free PMC article
- Cardiac proteostasis in obesity and cardiovascular disease.
Guerra J, Matta L, Bartelt A.
Herz. 2024 Mar;49(2):118-123. doi: 10.1007/s00059-024-05233-6. Epub 2024 Feb 8. PMID: 38329532 Free PMC article. Review.
- Treatment with siRNAs is commonly associated with GPX4 up-regulation and target knockdown-independent sensitization to ferroptosis.
von Mässenhausen A, Schlecht MN, Beer K, Maremonti F, Tonnus W, Belavgeni A, Gavali S, Flade K, Riley JS, Zamora Gonzalez N, Brucker A, Becker JN, Tmava M, Meyer C, Peitzsch M, Hugo C, Gembardt F, Angeli JPF, Bornstein SR, Tait SWG, Linkermann A.
Sci Adv. 2024 Mar 15;10(11):eadk7329. doi: 10.1126/sciadv.adk7329. Epub 2024 Mar 15. PMID: 38489367 Free PMC article.
- A tangible method to assess native ferroptosis suppressor activity.
Nakamura T, Ito J, Mourão ASD, Wahida A, Nakagawa K, Mishima E, Conrad M.
Cell Rep Methods. 2024 Feb 23:100710. doi: 10.1016/j.crmeth.2024.100710. Online ahead of print. PMID: 38401540 Free article.
- Tumor associated macrophages transfer ceruloplasmin mRNA to fibrosarcoma cells and protect them from ferroptosis.
Schwantes A, Wickert A, Becker S, Baer PC, Weigert A, Brüne B, Fuhrmann DC.
Redox Biol. 2024 Feb 17;71:103093. doi: 10.1016/j.redox.2024.103093. Online ahead of print. PMID: 38382185 Free PMC article.
- 7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.Nature. 2024 Jan 31. doi: 10.1038/s41586-023-06878-9. Online ahead of print.PMID: 38297129
- Lipids as mediators of cancer progression and metastasis.
Vogel FCE, Chaves-Filho AB, Schulze A.
Nat Cancer. 2024 Jan;5(1):16-29. doi: 10.1038/s43018-023-00702-z. Epub 2024 Jan 25. PMID: 38273023 Review.
- Membrane Epilipidome-Lipid Modifications, Their Dynamics, and Functional Significance.
Penkov S, Fedorova M.
Cold Spring Harb Perspect Biol. 2024 Jan 22:a041417. doi: 10.1101/cshperspect.a041417. Online ahead of print. PMID: 38253416
- Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle.
Sonsalla G, Malpartida AB, Riedemann T, Gusic M, Rusha E, Bulli G, Najas S, Janjic A, Hersbach BA, Smialowski P, Drukker M, Enard W, Prehn JHM, Prokisch H, Götz M, Masserdotti G.
Neuron. 2024 Jan 17:S0896-6273(23)00978-9. doi: 10.1016/j.neuron.2023.12.020. Online ahead of print. PMID: 38266647 Free article.
