2022
- Mitochondrial ferritin expression in human macrophages is facilitated by thrombin-mediated cleavage under hypoxia.Fuhrmann DC, Becker S, Brüne B.
FEBS Lett. 2022 Nov 23. doi: 10.1002/1873-3468.14545. Online ahead of print.PMID: 36416578
- Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals.Barayeu U, Schilling D, Eid M, Xavier da Silva TN, Schlicker L, Mitreska N, Zapp C, Gräter F, Miller AK, Kappl R, Schulze A, Friedmann Angeli JP, Dick TP.
Nat Chem Biol. 2022 Sep 15. doi: 10.1038/s41589-022-01145-w. Online ahead of print.PMID: 36109647
- Gasdermin D-deficient mice are hypersensitive to acute kidney injury.Tonnus W, Maremonti F, Belavgeni A, Latk M, Kusunoki Y, Brucker A, von Mässenhausen A, Meyer C, Locke S, Gembardt F, Beer K, Hoppenz P, Becker JU, Hugo C, Anders HJ, Bornstein SR, Shao F, Linkermann A. Cell Death Dis. 2022 Sep 15;13(9):792. doi: 10.1038/s41419-022-05230-9.PMID: 36109515 Free PMC article.
- A non-canonical vitamin K cycle is a potent ferroptosis suppressor.Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada KI, Wanninger J, ZilkaO, Sato E, Feederle R, Hass D, Maida A, Mourão ASD, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M.
Nature. 2022 Aug;608(7924):778-783. doi: 10.1038/s41586-022-05022-3. Epub 2022 Aug 3.PMID: 35922516
- Intrinsic and Extrinsic Limitations to the Design and Optimization of Inhibitors of Lipid Peroxidation and Associated Cell Death.Farmer LA, Wu Z, Poon JF, Zilka O, Lorenz SM, Huehn S, Proneth B, Conrad M, Pratt DA.
J Am Chem Soc. 2022 Aug 17;144(32):14706-14721. doi: 10.1021/jacs.2c05252. Epub 2022 Aug 3.PMID: 35921655
- Nutritional and Metabolic Control of Ferroptosis.Mishima E, Conrad M.
Annu Rev Nutr. 2022 Aug 22;42:275-309. doi: 10.1146/annurev-nutr-062320-114541. Epub 2022 Jun 1.PMID: 35650671 Review.
- Commonly Used Alkylating Agents Limit Persulfide Detection by Converting Protein Persulfides into Thioethers.Schilling D, Barayeu U, Steimbach RR, Talwar D, Miller AK, Dick TP.
Angew Chem Int Ed Engl. 2022 Jul 25;61(30):e202203684. doi: 10.1002/anie.202203684. Epub 2022 May 24.PMID: 35506673
- Glioblastoma Relapses Show Increased Markers of Vulnerability to Ferroptosis.Kram H, Prokop G, Haller B, Gempt J, Wu Y, Schmidt-Graf F, Schlegel J, Conrad M, Liesche-Starnecker F.
Front Oncol. 2022 Apr 21;12:841418. doi: 10.3389/fonc.2022.841418. eCollection 2022.PMID: 35530303
- Epithelial-mesenchymal transition and H2O2 signaling - a driver of disease progression and a vulnerability in cancers
Milton AV, Konrad DB.
Biol Chem. 2022 Jan 17;403(4):377-390. doi: 10.1515/hsz-2021-0341. Print 2022 Mar 28. PMID: 35032422 Review.
- The arginine methyltransferase PRMT7 promotes extravasation of monocytes resulting in tissue injury in COPD.Günes Günsel G, Conlon TM, Jeridi A, Kim R, Ertüz Z, Lang NJ, Ansari M, Novikova M, Jiang D, Strunz M, Gaianova M, Hollauer C, Gabriel C, Angelidis I, Doll S, Pestoni JC, Edelmann SL, Kohlhepp MS, Guillot A, Bassler K, Van Eeckhoutte HP, Kayalar Ö, Konyalilar N, Kanashova T, Rodius S, Ballester-López C, Genes Robles CM, Smirnova N, Rehberg M, Agarwal C, Krikki I, Piavaux B, Verleden SE, Vanaudenaerde B, Königshoff M, Dittmar G, Bracke KR, Schultze JL, Watz H, Eickelberg O, Stoeger T, Burgstaller G, Tacke F, Heissmeyer V, Rinkevich Y, Bayram H, Schiller HB, Conrad M, Schneider R, Yildirim AÖ.
Nat Commun. 2022 Mar 14;13(1):1303. doi: 10.1038/s41467-022-28809-4.PMID: 35288557
- NFE2L1-mediated proteasome function protects from ferroptosis.Kotschi S, Jung A, Willemsen N, Ofoghi A, Proneth B, Conrad M, Bartelt A.
Mol Metab. 2022 Mar;57:101436. doi: 10.1016/j.molmet.2022.101436. Epub 2022 Jan 6.PMID: 34999280
- Persister cancer cells: Iron addiction and vulnerability to ferroptosis.Rodriguez R, Schreiber SL, Conrad M.
Mol Cell. 2022 Feb 17;82(4):728-740. doi: 10.1016/j.molcel.2021.12.001. Epub 2021 Dec 28.PMID: 34965379 Review.
- Ferroptosis in Cancer Immunotherapy—Implications for Hepatocellular Carcinoma.Kusnick, J, Bruneau, A, Tacke, F, Hammerich, L.
Immuno, 2(1) 2022, 185-217. doi.org/10.3390/immuno2010014
